Establishing a Connection Between Heredity and Environmental Factors in Lung Cancer Development

Genetic factors, or inherited characteristics, are known to affect a person’s predisposition to lung cancer as much as environmental factors, most notably smoking. However, the interaction between one’s genetic composition and whether he or she smokes is in itself related to the development of this dreaded disease.

This interaction was discovered in a study conducted by a research team at Dartmouth College. The findings of the study showed that three variations in human DNA serve as the primary instigators in increasing a person’s susceptibility to lung cancer. These characteristics have been referred to as “biomarkers,” which can prove vital when it comes to dealing with cancer in certain patients. The data used in the study was provided by the OncoArray Consortium research network but is similar to the research currently being conducted by the technology firm Tempus.

Based on the study, the risk of developing lung cancer can be categorized to determine who will develop the disease and, in the event this occurs, of establishing treatment options. The one shortcoming of the study is that is was restricted to Caucasians and therefore may not extend to other ethnic groups with different genetic histories. According to Yafang Li, who headed the study, this issue could reduce its effectiveness. He added that the study could be expanded as more data becomes available. The findings of his team have been published in Carcinogenesis, a journal that deals with cancer issues.

The collection and study of molecular data is also the objective of Tempus. Based in Chicago, the firm was founded in 2016 by Eric Lefkofsky and a fellow entrepreneur. Lefkofsky was motivated to establish the firm through his personal commitment to help others diagnosed with cancer. In its quest to improve the diagnosis and treatment of malignant diseases, Tempus has collaborated with such medical facilities as the Mayo Clinic, the Cleveland Clinic and the University of Michigan.

Born 47 years ago in Detroit, Lefkofsky launched his business career as a carpet salesman at the University of Michigan, which also happened to be his alma mater. He and a friend would later purchase an apparel company in Madison, Wis. Lefkofsky would over a period of years help establish a number of businesses, including InnerWorkings, a marketing firm, and the financial company Lightbank.

Outside his business activities, Lefkofsky serves on the board of directors at Children’s Memorial Hospital, the Art Institute of Chicago and the Museum of Science and Industry. He also teaches university-level classes in the fields of business and entrepreneurship.

How Fabletics Is Staying Ahead In the Women Sportswear Market

Women are often left with two options when choosing the athletic-wear they need to buy. These options are either fashionable or affordable. Looking at this now, it is quick to notice that the women’s sportswear has long had a significant gap between functionality and fashion. In 2010, when the consumption of women’s active sportswear reached its peak, Don Ressler and Adam Goldenberg co-founded Fabletics. When they established this company, their primary objective was to meet the demands that the women required, so they developed their unique niche. Fabletics has been providing Women from all over the world with functional and affordable activewear. They’ve taken their business to higher levels by offering fashionable sportswear, a niche market that other players in the sector had been ignoring.

Adam and Don teamed up and revolutionized the industry in a rather ingenious method; instead of focusing on the current market needs, Fabletics concentrated their efforts on the creation of Sportswear women have always wanted. Through consumer tests, Fabletics was able to interview women and other focus groups. By the end of this, it was a consensus that the sportswear market was facing the same problems across the board. Some of the issues that were addressed are the fact that designers and key industry players had been long producing sportswear that was expensive, garnish and at times Ill-fitting. To further compile on these issues, most of the clothing created for the women market had dismal quality. When a person would finally put together an outfit matching their tastes and requirements, they’d almost always end up spending a fortune on them.

What sets Fabletics aside from most of its competitors is the fact that they have a tremendous online presence together with strong support from the grassroots. Fabletics was able to use Kate Hudson’s exemplary communication skills and charisma to market themselves online at the right time successfully. The success of their online marketing surpassed expectations as Fabletics outperformed most companies using traditional retail marketing strategies. Other than unique marketing that addressed various niche markets, Fabletics developed a creative discount system that has an appeal to the company’s clients. All this is evident when looking at the fact that Fabletics VIP costs only $50 each month.

Clients who subscribe to the VIP service often receive tailor-made services and discounted clothing prices. The company also provides free shipping and reward points for purchases to their clients accepted as VIP members.

How Glen Wakeman is a Source of Motivation to Young Entrepreneurs.

Glen Wakeman is the current chief executive officer of the LaunchPad Holding Company. LaunchPad Holding is a SAAS company co-founded in the year 2015. Mr. Wakeman is a seasoned businessman and a finance expert for two decades now. He is an Economics and Finance graduate from the Scranton University in the year 1981. He has an MBA specializing in Finance from the University of Chicago.

Throughout his career, Glen Wakeman has been known for his entrepreneurial spirit, business revolutionary, and his mentoring skills. Most of his works revolve around setting up of new companies and developing new performance methods. During his entire career, Mr. Wakeman has worked in various institutions like the GE Capital; he is also the founder member of Nova Four. He has also been in various management groups serving as CEO, President and a member of the Board of Directors among other administrative positions.

Glen Wakeman is the brain behind the five step performance methodology (AffiliateDork). The performance system focuses on human capital, risk management, power, control as well as execution in business. Being a writer and a successful investor, Mr. Wakeman has been the source of motivation to many future entrepreneurs. His diverse knowledge on various subjects; corporate management, emerging market trends, and divestitures makes Glen Wakeman a successful marketing strategist capable of providing insightful advice at different executive groups.

As an active participant in the transformative business opportunities, Mr. Wakeman is well versed with the leadership system in various global affairs. He provides strategic advice to various entrepreneurs and investors on angel investing, capital raising and international financing platforms. As a resident of more than six countries, Wakeman has been able to successfully run business activities in more than 30 regions across the globe.

Glen Wakeman attributes the start of LaunchPad Holding Inc. to his passion for matching several ideas with money. He argues that great ideas are generated from some of the most talented start-ups, he, therefore, cannot understand why such ideas end up failing. He argues that the main reason behind this failure is lack of a clear plan surrounding the entire idea. People are still not able to differentiate between an idea and a plan.

More about Glen Wakeman at https://ideamensch.com/glen-wakeman/

Equities First Holdings sees growing demand for stock loans as tight credit markets make borrowing tougher

Equities First Holdings has proved itself to become one of the most competent companies dealing in the stock-based loans. As a matter of fact, no one knows the ways of the company while we may think they are working. The company is now working to sustain the whole world in the issuance of stock-based loans targeting the rich individuals and companies. For startups, capital is one of the most crucial things to enable the world develops high-end capabilities. As a matter of fact, we might consider its use in the development of easy functionality. For this reason, people end up working at the premises of Equities First Holdings.

The use of stock-based loans is increasing in this fast world. While the economy is not stable, banks and other credit-based companies are tightening their lending capabilities. For the banks, they also increase the interest rates to amounts that scare away most of the applicants. As a matter of fact, no one has a better understanding of the ways that a person does his things. For the company, they always endeavor to sustain the economy and those in need of fast working capital in a harsh economic crisis. For you to secure fast working capital from the company, all you need to do is to get better results through the working of these loans. For this reason, you might take care of your needs and more important information click here .

Since the company was incepted in 2002, it has completed more than 2000 transactions. This translates to the fact that Equities First Holdings has issued more than $2 billion as loans to their clients. For his reason, they have worked to determine the workability of better results through the issuance of fast working capital. While this is a major achievement for Equities First Holdings, they also consider this as daily business conducted on a working day.

More visit: https://beta.companieshouse.gov.uk/company/08120457

The Star in Clay Siegall

Clay Siegall in his WordPress page has written a lot of educative posts. On 6th March, he wrote on what to do when a Lyme-infested tick bites you. He was driven to write due to the spread of Lyme in the mid-Atlantic region. The figures from research show that the number of Lyme cases reported have doubled from 2001 to 2015. Clay also explained on the effects of Lyme, which include flu like symptoms and arthritis. He further explained that one should always be on the lookout for ticks. He gave a guide on what to do when one spots a tick; relax, use tweezers to pull out the head of the tick, check whether the tick you picked is from a Lyme infested area, take the tick to a lab for study and monitor to see if you have got any Lyme related infection.

 

On 4th March 2017, Siegall wrote on how a doctor launched a vision to help astronauts’ eyeballs. Siegall explained how a doctor had done research and found out that after spending too much in space, one’s vision usually changes; one generally struggles to read. The scientific explanation to this was that while in space, the fluid around the heart moves to the head and causes damage to one’s vision. This was due to the anti-gravity state, but doctors were working to resolve the issue.

 

Clay B. Siegall is the co-founder of Seattle Genetics, which he founded in the year 1998, and is the Chairman of the Board, the company’s President, and the Chief Executive Officer. He is a scientist with emphasis on targeted cancer therapies. He built his foundation with the main aim of attaining scientific innovation, religious research and drug development practices. Under Clay’s leadership, the company has been guided to securing the 2011 FDA approval of its first ADC products. Seattle Genetics has collaborated with Takeda Pharmaceutical Company, and is now a brand approved in 65 countries. Dr. Siegall has also led Seattle Genetics’ fund raising activities by raising more than $1.2 billion. Previously, Dr. Siegall had worked with the National Cancer Institute, Bristol-Myers Squibb Pharmaceutical Research Institute, and the National Institutes of Health.